A systematic review on the treatment of androgenetic alopecia

Androgenetic Alopecia: a Review and Emerging Treatments

Androgenetic Alopecia (AGA) is the most common noncicatricial alopecia that leads to the progressive miniaturization of the hair follicle. Scalp terminal hairs are converted into vellus hairs, primarily due to two factors: genetic predisposition and hormonal stimulation. The incidence and prevalence of AGA increases with age. The onset of AGA is gradual, and when this pathology progresses, the ...

Androgenetic Alopecia

Androgenetic alopecia and current methods of treatment.

Androgenetic alopecia (AGA) is a common dermatological condition affecting both men and women. In the case of men, up to 30% over the age of 30 and more than 50% over the age of 50 are affected. AGA also affects women although clinical signs are usually milder and associated with diffuse thinning of the scalp hair. AGA invariably causes serious psychological problems especially in women. By far...

Topical Melatonin for Treatment of Androgenetic Alopecia

BACKGROUND In the search for alternative agents to oral finasteride and topical minoxidil for the treatment of androgenetic alopecia (AGA), melatonin, a potent antioxidant and growth modulator, was identified as a promising candidate based on in vitro and in vivo studies. MATERIALS AND METHODS One pharmacodynamic study on topical application of melatonin and four clinical pre-post studies wer...

New Medical Treatment for Androgenetic Alopecia

Dihydrotestosterone(DHT) has played the pathogenic role in androgenetic alopecia. Patients with genetic deficiency of 5 alpha-reductase type II enzyme, which converts testosterone to DHT, do not have androgenic alopecia. The conversion of testosterone to DHT at hair follicles leads to miniaturization. In scalp biopsy, the tissue DHT level is significantly increased in balded area than non-balde...